Welcome, my name is Robert Rojas and I am an undergraduate MCD Biology Research Student Scientist at the University of California Santa Cruz

"THOSE WHO DARE TO FAIL MISERABLY CAN ACHIEVE GREATLY" -JFK

In this web page, you will find a little about me and as you scroll down I will generally explain concepts that revolve around MCD Biology topics.

Check out my first program @ "HI THERE"


THE BIOLOGY:

Topic: Neuroscience: Synaptic Transmission

  1. The synthesized neurotransmitters are packaged into vesicles.
  2. When an action potential invades a presynaptic terminal, depolarization of the neuronal cell causes opening of the Voltage-gated Calcium Cation Channels.
  3. This creates an influx of calcium cations(due to concentration differences between outside and inside of the cell), which rushes in rapidly.
  4. The increase of calcium within the neuronal cell terminal causes vesicle fusion with the membrane of the cell.
  5. Once the vesicle fuses with the membrane, neurotransmitters are then released into the synaptic cleft. (Release process known as exocytosis)
  6. Next, neurotransmitters in the synaptic cleft may bind to recptors on postsynaptic cells.
  7. This opens or closes postsynaptic channels, allowing postsynaptic current to flow into the post synaptic cell.
  8. Neurotransmitters are typically removed by glial cell reuptake or enzymatic degradation.
  9. Retrival of the membrane is completed through a process called endocytosis.
(More topics and explantions will be discussed monthly.)

Refrences:

Basic Neurochemistry: Molecular, Cellular and Medical Aspects
For any further help, suggestions on topics, comments, and/or concerns, emails are warmly welcomed
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